School of Chemistry
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Congrats to Jess and Casper on the publication of their PCCP paper “Improved NOE fitting for flexible molecules based on molecular mechanics data – a case study with S-adenosylmethionine”. In a nutshell it highlights the improvements that are possible by … Continue reading
Jess has just submitted the final version of her PhD thesis on “Optimisation and Application of Interproton Distances Measured by NOE Spectroscopy” and is awaiting the official “You can call yourself Dr”. Well done Dr Bame!
Well done Siying! Her work has just been published, in Nature, on the re-evaluation of the stereochemistry of Baulamycins A & B- working out the correct isomer from 128 possible diastereomers from a combination of NMR+computation (which eliminated 120 diastereomers) … Continue reading
Iyke’s latest paper outlines EXACT-PSYCHE – Broadband homodecoupled 1H NMR spectra, collected up to 4-times faster than the standard experiment (with some clever IST-based processing from our Krzysztof and Alexandra (University of Warsaw) and Carlos (MestreLab Research). It’s a nice … Continue reading
[A wandering thought from Craig….] I always wanted to be either a rocket scientist or cure cancer….. I made a good start, when the compound I worked on during my PhD (tetranitromethane) was indeed studied as a rocket fuel additive. … Continue reading
Well, if you want to know I suggest you have a look at Jonathan Clayden’s latest report in Chemical Science. It’s a beautiful exposition of chemical synthesis, analysis and computation, combined to understand the structure and dynamics of ‘faults’ in … Continue reading
Claire’s first paper from her PhD research, shared with Alex and Alice from their undergraduate projects, has come out in The Analyst (http://pubs.rsc.org/en/content/articlepdf/2017/an/c6an02298g) today. A beautiful exposition of what NMR methods allow us to most efficiently, most easily and most accurately … Continue reading
Iyke passed his PhD viva on December 9th – having been grilled by Dr James Keeler and Professor Matt Crump. Congratulations Dr Ndukwe!
Iyke’s EXACT method for burst-sampled acquisition (see 14th July post below) in the direct dimension of NMR experiments has been extended in his latest paper to the reduction in duty-cycle of the demanding ASAP-HSQC experiment. The resulting EXACT ASAP-HSQC experiment can be acquired in … Continue reading
Craig has just presented a webinar for MestreLab Research SL on quantitative NOE analysis for small molecules. It gives an outline of how we (currently!) analyse NOE data to extract accurate interproton distances, looks at some of the problems which … Continue reading