Category Archives: Uncategorized
[A wandering thought from Craig….] I always wanted to be either a rocket scientist or cure cancer….. I made a good start, when the compound I worked on during my PhD (tetranitromethane) was indeed studied as a rocket fuel additive. … Continue reading
Well, if you want to know I suggest you have a look at Jonathan Clayden’s latest report in Chemical Science. It’s a beautiful exposition of chemical synthesis, analysis and computation, combined to understand the structure and dynamics of ‘faults’ in … Continue reading
Claire’s first paper from her PhD research, shared with Alex and Alice from their undergraduate projects, has come out in The Analyst (http://pubs.rsc.org/en/content/articlepdf/2017/an/c6an02298g) today. A beautiful exposition of what NMR methods allow us to most efficiently, most easily and most accurately … Continue reading
Iyke passed his PhD viva on December 9th – having been grilled by Dr James Keeler and Professor Matt Crump. Congratulations Dr Ndukwe!
Iyke’s EXACT method for burst-sampled acquisition (see 14th July post below) in the direct dimension of NMR experiments has been extended in his latest paper to the reduction in duty-cycle of the demanding ASAP-HSQC experiment. The resulting EXACT ASAP-HSQC experiment can be acquired in … Continue reading
Craig has just presented a webinar for MestreLab Research SL on quantitative NOE analysis for small molecules. It gives an outline of how we (currently!) analyse NOE data to extract accurate interproton distances, looks at some of the problems which … Continue reading
Iyke’s latest publication has just come out online – “EXtended ACquisition Time (EXACT) NMR—A Case for ′Burst′ Non-Uniform Sampling” describes a novel approach to Non-uniform sampling in the direct dimension of NMR spectra which allows us to extend the acquisition times … Continue reading
Catharine and Jess’s paper on NOE measurements being used to elucidate tiny changes in conformer populations with temperature has been accepted for publication in Chem Comm. They quantified changes of ~98:2 to ~96:4 in conformer populations with increasing temperature for … Continue reading
Iyke has published his work on increasing sensitivity and resolution in EXSIDE measurements: Pure-shift IMPRESS EXSIDE – Easy measurement of 1 H- 13C scalar coupling constants with increased sensitivity and resolution Sensitivity is increased up to 1000% in some of … Continue reading
Siying Zhong, fresh out of her Chemical Synthesis Centre for Doctoral Training bootcamp has joined the group. She is co-supervised for her PhD by Professor Varinder Aggarwal, and splits her time between synthesis with his group and NMR/computation with ours.