Stereochemistry in complex, flexible molecules

Well done Siying! Her work has just been published, in Nature, on the re-evaluation of the stereochemistry of Baulamycins A & B- working out the correct isomer from 128 possible diastereomers from a combination of NMR+computation (which eliminated 120 diastereomers) and synthesis (which narrowed it down to the right structure). Craig was hoping it would be his 100th paper (it was his 99th), but you can’t have everything……

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